ncRNA name | hsa-miR-92a |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | CD34 Cells |
Methods | qRT-PCR, microarray |
Expression pattern | down-regulated |
Functional description | Restoration of miR-92a levels in CD34(+) cells from patients with diabetes with DR reduced the inflammatory phenotype of these cells and the diabetes-induced propensity toward myeloid differentiation. Our studies suggest that restoring levels of miR-92a could enhance the usefulness of CD34(+) cells in autologous cell therapy. |
PubMed ID | 26283734 |
Year | 2015 |
Title | miR-92a Corrects CD34+ Cell Dysfunction in Diabetes by Modulating Core Circadian Genes Involved in Progenitor Differentiation. |
Drug-related ncRNA | NO |
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